The concept of gene therapy began to take shape in the 1970s and 1980s as researchers started exploring the potential of manipulating genes to treat genetic disorders. Early experiments involved techniques like recombinant DNA technology, which allowed scientists to isolate and modify genes.
The first significant application of gene therapy occurred in 1990 when a girl named Ashanti DeSilva received treatment for adenosine deaminase (ADA) deficiency, marking a milestone in modern gene therapy. This pioneering effort demonstrated that it was possible to introduce healthy genes into a patient's cells to correct a genetic disorder. Since then, gene therapy has evolved significantly, leading to various innovative treatments targeting a range of genetic conditions.
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